Fig. 1.
Scatterplots of significant relationships between reserve proxies and neuropsychological test scores. A) WRAT-4 and animal fluency (p = 0.04), the COWAT (p < 0.01), NAB (p = 0.04), and TMT A (p = 0.04). B) Residual episodic memory variance and TMT A (p < 0.01), TMT B (p < 0.01), and animal fluency (p < 0.01). C) Residual executive functioning variance and TMT A (p < 0.01) and NAB (p < 0.01). Statistical significance was defined by a false discovery rate adjusted p-value<0.05. Age, racial identity, CHII, and APOE genotype were included as covariates. Non-significant associations presented in Table 4 and Supplementary Table 1 not shown. CHII, cumulative head impact index; WRAT-4, Wide Range Achievement Test-4; COWAT, Controlled Oral Word Association Test; NAB, Neuropsychological Assessment Battery List Learning Long Delay Recall; TMT A, Trail Making Test Part A; TMT B, Trail Making Test Part B; REMV, residual episodic memory variance; REFV, residual executive functioning variance.