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. Author manuscript; available in PMC: 2022 Mar 16.
Published in final edited form as: Science. 2016 Apr 15;352(6283):363–365. doi: 10.1126/science.aaf0643

Fig. 3. Simple and highly similar organizational principles govern the architecture of the inner and outer rings of the NPC.

Fig. 3.

(A) Schematic representation of the branching motif formed by the different heterodimers. (B) Structural similarity of the Nup155-Nup93 dimer to the Nup107-Nup133 and Nup120-Nup85 dimers. The structures are shown in low-resolution representation within the corresponding segments of the tomographic map. Homologous Nups are colored identically. (C) Arrangement of the branching motifs within the NPC membrane-binding coat [homologous Nups are colored as in (B)]. (D) Schematic of the human NPC architecture (details are shown in figs. S9 to S11). Trailing lines indicate FG repeats.