Table 1.
Participant demographics and clinical characteristics. Participant data is provided separately for Dataset 1, Dataset 2, and the combined Longitudinal Dataset. Nine individuals with A-T are listed as “uncertain” in the A-T phenotype column as they are 6 years old or younger, and it is too early to make a determination
| Diagnosis | N | Age at start | Sex | Handedness | BARS (0–30) | CPCHILD (0–78) | Wheelchair use (N) | A-T phenotype (N) | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Median | Range | M | F | R | L | A | ||||||
| Dataset 1 (DS1), January-June 2020 | ||||||||||||
| A-T | 15 | 11.0 | 6.3–18.2 | 9 | 6 | 14 | 1 | 0 | 11.0–25.5 | N/A | 8 | Classic (15) |
| Control | 15 | 11.0 | 5.0–16.0 | 9 | 6 | 14 | 1 | 0 | 0 | N/A | 0 | N/A |
| Dataset 2 (DS2), January–August 2021 | ||||||||||||
| A-T | 30 | 10.8 | 2.6–20.0 | 18 | 12 | 26 | 2 | 2 | N/A | 20–72 | 13 |
Classic (20) Mild (1) Uncertain (9) |
| Control | 25 | 10.8 | 2.3–17.2 | 13 | 12 | 21 | 3 | 1 | N/A | 73–78 | 0 | N/A |
| Longitudinal Data (LD), data from DS1 and DS2 | ||||||||||||
| A-T | 14 | 10.9 | 6.3–18.2 | 9 | 5 | 13 | 1 | 0 | 11.0–25.5 | 20–72 | 7 | Classic (14) |
| Control | 13 | 11.0 | 5.0–16.0 | 8 | 5 | 12 | 1 | 0 | 0 | 75–78 | 0 | N/A |
*CPCHILD scores reported are for individuals 6–18 years of age
Abbreviations: A ambidextrous, BARS Brief Ataxia Rating Scale, CPCHILD Caregiver Priorities and Child Health Index of Life with Disabilities