Supplementary Table 2.

Factors predicting deterioration during hospital stay amongst those with no hypoxia at Baseline

	OR (95% CI), P
	Model-1	Model-2
Age (Reference: 18-45 years)
<18 years	0.78 (0.32-1.88), 0.578	0.5 (0.1-2.1), 0.365
45-60 years	2.1 (1.38-3.19), 0.001	1.4 (0.8-2.4), 0.188
>60 years	2.44 (1.52-3.91), <0.001	1.5 (0.8-2.7), 0.213
Male (Reference: Female)	1.53 (1.07-2.18), 0.02	1.1 (0.72-1.8), 0.588
Vaccinated	0.71 (0.48-1.05), 0.085	0.8 (0.49-1.3), 0.317
Comorbidities (Reference: No)
1	1.5 (1.02-2.22), 0.041	1.2 (0.7-1.9), 0.553
2 or more	2.13 (1.31-3.45), 0.002	1.4 (0.8-2.6), 0.258
Baseline COVID-19 severity (Reference: Mild)
Asymptomatic - No hypoxia	0.36 (0.14-0.94), 0.036
Moderate	2.22 (1.56-3.15), <0.001
Symptoms reported (Reference: No)
Dry cough	1.49 (1.05-2.1), 0.025
Gastrointestinal symptoms	1.95 (1.28-2.97), 0.002
Fever		2.3 (1.3-4), 0.003
Lab parameters (Reference: No)
Leucocyte count (Reference: Normal)
Leukopenia		0.5 (0.3-0.9), 0.026
Leukocytosis		2.3 (1.3-4.0), 0.003
D-Dimer >500 ng/ml (Reference: ≤500 ng/ml)		1.7 (1.0-3.0), 0.047
CRP >0.5 mg/dl (Reference: ≤0.5 mg/dl)		9.4 (3.7-24.0), <0.001
Creatinine >1.0 mg/dl (Reference: ≤1.0 mg/dl)		2.2 (1.2-3.9), 0.010

Notes: Model-1: Adjusting for baseline clinical parameters, Model-2: Model-1 plus baseline lab parameters·Age, gender and comorbidities are included in all the models·Only symptoms and lab parameters with significant P value are included in these final models. OR: Odds ratio, CI: Confidence interval, CRP: C-reactive protein