Table 3. Prevalence and incidence of EHR-derived AF by age, sex, and race/ethnicity, All of Us Research Program, 2017–2019.
| Prevalent AF | Incident AF | |||||||
|---|---|---|---|---|---|---|---|---|
| Age group | AF cases | Total | Prevalence (%) | Odds Ratio (95% CI)* | AF cases | Person-years | Incidence** | Hazard Ratio (95% CI)*** |
| <40 | 71 | 23,285 | 0.3 | 1 (Ref.) | <20 | 32,271 | <0.6 | 1 (Ref.) |
| 40–49 | 160 | 12,609 | 1.3 | 4.2 (3.2, 5.6) | <20 | 17,006 | <1.2 | 2.9 (1.4, 5.9) |
| 50–59 | 466 | 19,326 | 2.4 | 8.0 (6.2, 10.3) | 57 | 25,830 | 2.2 | 6.0 (3.2, 11.2) |
| 60–69 | 1150 | 21,016 | 5.5 | 17.8 (14.0, 22.6) | 110 | 26,893 | 4.1 | 10.4 (5.7, 19.0) |
| 70–79 | 1445 | 12,979 | 11.1 | 35.8 (28.1, 45.5) | 116 | 15,314 | 7.6 | 17.4 (9.6, 31.7) |
| 80–89 | 593 | 3,103 | 19.1 | 66.2 (51.5, 85.1) | 41 | 3,232 | 12.3 | 28.1 (14.7, 53.7) |
| Sex | ||||||||
| Female | 1,751 | 57,439 | 3.0 | 1 (Ref.) | 170 | 76,083 | 2.2 | 1 (Ref.) |
| Male | 2,134 | 34,879 | 6.1 | 1.9 (1.8, 2.0) | 184 | 44,464 | 4.1 | 1.7 (1.4, 2.1) |
| Race / ethnicity | ||||||||
| Hispanic | 46 | 2,496 | 1.8 | 0.89 (0.66, 1.2) | <20 | 3,372 | <5.9 | 1.4 (0.71, 2.9) |
| NH Asian | 62 | 3,444 | 1.8 | 0.63 (0.49, 0.82) | <20 | 4,850 | <4.1 | 0.41 (0.15, 1.1) |
| NH Black | 544 | 24,435 | 2.2 | 0.64 (0.58, 0.71) | 48 | 31,102 | 1.5 | 0.55 (0.40, 0.76) |
| NH White | 3,233 | 61,943 | 5.2 | 1 (Ref.) | 294 | 81,222 | 3.6 | 1 (Ref.) |
* Results from binary logistic regression including age category, sex and race as independent variables in the same model.
** Per 1,000 person-years.
*** Results from Cox regression including age category, sex and race as independent variables in the same model.