Table 13. Concordance of F1CDx and FoundationOne® for platform-wide variants.
| F1CDx+/F1 LDT+ | F1CDx-/F1 LDT+ | F1CDx+/F1 LDT- | F1CDx-/F1 LDT- | PPA | NPA | |
|---|---|---|---|---|---|---|
| All variants | 2246 | 33 | 46 | 322890 | 98.6% | 99.99% |
| All SVs | 1984 | 19 | 23 | 299099 | 99.1% | 99.99% |
| SUBs | 1692 | 10 | 19 | 254854 | 99.4% | 99.99% |
| INDELs | 292 | 9 | 4 | 44245 | 97.0% | 99.99% |
| All CNA | 230 | 14 | 22 | 19204 | 94.3% | 99.9% |
| Amplifications | 157 | 10 | 12 | 14671 | 94.0% | 99.9% |
| Losses | 73 | 4 | 10 | 4533 | 94.8% | 99.8% |
| Rearrangements | 32 | 0 | 1 | 4587 | 100.0% | 99.98% |
CNA = copy number alterations; F1CDx = FoundationOne®CDx; F1 LDT = FoundationOne® Laboratory Developed Test; INDEL = insertion/deletion; NPA = negative percent agreement; PPA = positive percent agreement; SV = short variants; SUB = substitutions.