Fig. 2. Hydrophobic packing of triblock (A and B) and diblock (C) peptide amphiphiles as mono- and bilayers, respectively. (A) Janus nanosheets obtained from peptides with segregated hydrophobic blocks (Phe₆vs. C10), which favour parallel monomer alignment by Phe H-bonding and π–π stacking in two perpendicular axes. Reprinted with permission from ref. 70. Copyright 2017 American Chemical Society. (B) Steric zipping of complementary hydrophobic interfaces between adjacent β-sheets. Reprinted with permission from ref. 71. (C) Amphiphilic cyclic peptide with alternating (d/l) chirality with 2D self-assembly via inter-backbone axial H-bonding (3) and lateral Leu zippers between nanotubes (4). Adapted with permission from ref. 65. Copyright 2019 American Chemical Society.