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. 2022 Mar 2;16:789524. doi: 10.3389/fnbeh.2022.789524

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Copyright © 2022 Chen, Shen, Liu, Xu and Wang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The influence of DHK on the mTOR phosphorylation in the PFC of mice. mTOR and pmTOR protein expression were determined by Western blot. Representative western blot (A) and quantification (B,C) of fold changes in the protein levels of pmTOR and mTOR in the PFC of mice. The data are expressed as means ± SEM; n = 3; *P < 0.05 compared with vehicle + vehicle + non-stressed group; ^##P < 0.01 compared with vehicle + vehicle + CUMS group; ^@@P < 0.01 compared with ketamine + vehicle + CUMS group.