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. 2022 Mar 16;8(11):eabj6526. doi: 10.1126/sciadv.abj6526

Fig. 2. HSF2 shares chromatin occupancy sites with HSF1 in cancer cells.

Fig. 2.

(A and F) ChIP-seq for HSF2 or HSF1 in the indicated cell line. Dual tracks indicate biological replicates. (B and G) Enriched motifs of ChIP peaks. (C and H) Example ChIP-seq tracks for HSF2 and HSF1 at five loci implicated in HSF cancer programs. (D, E, I, and J) ChIP-seq tracks for HSF1 or HSF2 in HSF knockout cells as indicated. These data merged all replicates for ease of visualization. WT, wild-type, parental cell lines. c1 and c2 represent cell lines expanded from a single wild-type cell clone as control for clonal CRISPR knockouts.