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. 2022 Mar 16;8(11):eabl6989. doi: 10.1126/sciadv.abl6989

Table 1. Overview of considered hallucinogenic drug agents.

IV, intravenous.

Drug chemical class Drug name Drug effect class Number of
testimonials
Estimated
duration
Average
duration
(hours)
Dosage range Route of
administration
Source
Tryptamine 5-MeO-DMT Psychedelic 282 5–20 min 0.2 2–15 mg Smoked erowid.org
DMT Psychedelic 531 5–20 min 0.2 15–60 mg Smoked
DPT Psychedelic 148 2–4 hours 3 100–250 mg Oral
Psilocin Psychedelic 597 3–6 hours 4.5 10–20 mg Oral
5-MeO-MiPT Psychedelic 71 4–6 hours 5 2–7 mg Oral
5-MeO-DiPT Psychedelic 208 4–8 hours 6 6–12 mg Oral
DiPT Psychedelic 54 6–8 hours 7 25–100 mg Oral
5-MeO-TMT Psychedelic 109 5–10 hours 7.5 75–150 mg Oral
Phenethylamine 2C-D Psychedelic 47 4–6 hours 5 20–60 mg Oral
2C-B Psychedelic 204 4–8 hours 6 10–35 mg Oral and insufflated
2C-C Psychedelic 64 4–8 hours 6 20–40 mg Oral
2C-T-2 Psychedelic 118 6–8 hours 7 12–25 mg Oral
2C-P Psychedelic 58 5–10 hours 7.5 6–10 mg Oral
25I-NBOMe Psychedelic 150 6–10 hours 8 50–1200 mcg Oral
2C-I Psychedelic 391 6–10 hours 8 14–22 mg Oral
2C-E Psychedelic 303 8–12 hours 10 10–25 mg Oral
Mescaline Psychedelic 136 10–12 hours 11 200–400 mg Oral
2C-T-7 Psychedelic 173 8–15 hours 11.5 10–30 mg Oral
Lysergamide LSD Psychedelic 1173 5–12 hours 8.5 50–200 mcg Oral
Diterpenoid Salvinorin A Dissociative
hallucinogen
199 5–30 min 0.3 200 mcg–1 mg Smoked and oral
Arylcyclohexylamine Ketamine Dissociative anesthetic 405 45–90 min 1 100–500 mg Insufflated, oral, and IV
Amphetamine MDA Entactogen 79 4–6 hours 5 80–160 mg Oral
MDMA Entactogen 1155 4–6 hours 5 80–150 mg Oral
DOM Psychedelic 36 14–20 hours 17 3–10 mg Oral
DOI Psychedelic 34 16–30 hours 23 1.5–3 mg Oral
DOB Psychedelic 45 18–30 hours 24 1–3 g Oral
Indole alkaloid Ibogaine Dissociative psychedelic 80 18–36 hours 26 1–1.5 g Oral