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The effect of the age on the endothelium-dependent vasorelaxation of the thoracic aorta in Wistar-Kyoto (WKY) (a) and spontaneously hypertensive rats (SHR) (b). The results are presented as the mean ± SEM of n = 8–10 rats, and differences between groups were analyzed by two-way analysis of variance (ANOVA) with the Bonferroni post hoc test on ranks. +p < 0.05 vs. 7-week-old rats, xp < 0.05 vs. 20-week-old rats.
