Figure 1.

Experimental setup for soil extract exposure of mice. The soil exposure was performed in 6–7‐week‐old Female mice (C57BL/6) for 1 h each day to normal mouse bedding alone (control group) or bedding mixed with 50 ml of soil powder and then returned to their normal cage. Soil dose was measured using 50 mlSchott glass bottles (Kisker Biotech GmbH & Co. KG). This procedure was repeated five times a week for 3 weeks. Identical experiment was performed twice to obtain a total of eight mice per treatment group. At Day 21 the animals were euthanized, and organ samples were collected