Table 3.
Changes in GFAp, NfL and tau after diving
| Sample 1: before first dive | Absolute value (n = 32) | Absolute change compared to sample 1 (n = 32) | p-value |
|---|---|---|---|
| GFAp (pg mL−1) | 60.3 (26.2) | ||
| 51.9 (31.2; 139.2) | |||
| NfL (pg mL−1) | 7.84 (7.72) | ||
| 6.12 (3.4; 47.79) | |||
| Tau (pg mL−1) | 1.70 (0.89) | ||
| 1.5 (0.4; 4.3) |
| Sample 2: 30–45 min after first dive | Absolute value (n = 32) | Absolute change compared to sample 1 (n = 32) | p-value |
|---|---|---|---|
| GFAp (pg mL−1) | 56.6 (24.0) | −3.69 (10.08) | 0.045 |
| 49.4 (29; 139) | −2.90 (−30.21; 20.22) | ||
| (−7.29; −0.06) | |||
| NfL (pg mL−1) | 7.75 (8.28) | −0.09 (0.92) | 0.61 |
| 5.66 (3.21; 51.01) | −0.24 (−1.29; 3.22) | ||
| (−0.40; 0.24) | |||
| Tau (pg mL−1) | 1.89 (0.84) | 0.18 (0.73) | 0.17 |
| 1.86 (0.39; 3.68) | 0.20 (−2.08; 2.22) | ||
| (−0.08; 0.44) |
| Sample 3: 120 min after first dive | Absolute value (n = 32) | Absolute change compared to sample 1 (n = 32) | p-value |
|---|---|---|---|
| GFAp (pg mL−1) | 56.5 (20.9) | −3.82 (12.88) | 0.11 |
| 55.4 (26.5; 128.5 | −3.31 (−40.28; 15.25) | ||
| (−8.52; 0.87) | |||
| NfL (pg mL−1) | 8.11 (8.33) | 0.271 (1.11) | 0.18 |
| 6.4 (3.05; 51.61) | 0.11 (−1.68; 3.83) | ||
| (−0.13; 0.67) | |||
| Tau (pg mL−1) | 2.18 (1.47) | 0.48 (1.03) | 0.0008 |
| 1.84 (0.45; 8.13) | 0.27 (−1.03; 5.21) | ||
| (0.15; 0.82) |
| Sample 4: before second dive (48 h after the first dive) | Absolute value (n = 32) | Absolute change compared to sample 1 (n = 32) | p-value |
|---|---|---|---|
| GFAp (pg mL−1) | 57.3 (20.6) | −3.03 (14.16) | 0.24 |
| 58.3 (33; 135.7) | −5.83 (−33.76; 27.82) | ||
| (−8.18; 2.14) | |||
| NfL (pg mL−1) | 8.11 (8.43) | 0.27 (2.03) | 0.55 |
| 6.02 (3.6; 51.25) | −0.28 (−1.56; 9.62) | ||
| (−0.38; 0.97) | |||
| Tau (pg mL−1) | 1.68 (0.81) | −0.02 (0.50) | 0.81 |
| 1.54 (0.58; 3.16) | 0.01 (−1.36; 0.86) | ||
| (−0.20; 0.16) |
| Sample 5: 30–45 min after second dive | Absolute value (n = 32) | Absolute change compared to sample 4 (n = 32) | p-value |
|---|---|---|---|
| GFAp (pg mL−1) | 56.2 (19.5) | −1.14 (8.34) | 0.45 |
| 55 (31.5; 127.6) | −0.88 (−14.61; 13.69) | ||
| (−4.21; 1.91) | |||
| NfL (pg mL−1) | 7.84 (7.64) | −0.27 (2.07) | 0.48 |
| 6.16 (3.44; 47.66) | −0.11 (−7.54; 6.38) | ||
| (−1.01; 0.45) | |||
| Tau (pg mL−1) | 2.11 (1.32) | 0.42 (0.92) | 0.0098 |
| 1.89 (0.53; 5.27) | 0.24 (−1.67; 3.09) | ||
| (0.10; 0.76) |
| Sample 6: 120 min after second dive | Absolute value (n = 32) | Absolute change compared to sample 4 (n = 32) | p-value |
|---|---|---|---|
| GFAp (pg mL−1) | 58.1 (20.3) | 0.80 (10.06) | 0.65 |
| 57.3 (30.5; 138) | 0.95 (−18.24; 22.63) | ||
| (−2.81; 4.39) | |||
| NfL (pg mL−1) | 8.01 (8.38) | −0.10 (1.49) | 0.84 |
| 6.12 (3.05; 51.95) | 0.19 (−7.31; 1.94) | ||
| (−0.61; 0.34) | |||
| Tau (pg mL−1) | 2.23 (1.56) | 0.54 (1.20) | 0.0041 |
| 1.96 (0.6; 6.74) | 0.12 (−0.90; 4.91) | ||
| (0.14; 0.97) |
Mean (SD)/median (min; max)/(95% CI for mean using the inversion of Fisher’s non-parametric permutation test) is presented. For comparison within groups the Fisher’s non-parametric permutation test for matched pairs was used