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. 2022 Feb 14;36(3):301–313. doi: 10.1007/s40263-021-00890-1

Table 5.

Summary of drug-related adverse events (AEs) (safety set)

HSK3486 (n = 135) Propofol (n = 132) P-value
Increased serum bilirubin 2 (1.5) 3 (2.3) 0.9798
Somnolence 2 (1.5) 3 (2.3) 0.9798
Dizziness 6 (4.4) 8 (6.1) 0.5536
Hypoxia 8 (5.9) 3 (2.3) 0.1332
Hiccups 0 (0.0) 1 (0.8) 0.494
Erythematous rash 0 (0.0) 1 (0.8) 0.494
Rash 1 (0.7) 0 (0.0) 1.000
Pruritus 0 (0.0) 2 (1.5) 0.244
Cry 1 (0.7) 0 (0.0) 1.000
Pain on injection 6 (4.4) 52 (39.4) < 0.001
Vomiting 0 (0.0) 1 (0.8) 0.494
Bradycardia/sinus bradycardia 10 (7.4) 11 (8.3) 0.823
Hypotension 30 (22.2) 37 (28.0) 0.323

Data are given as numbers with percentage in parentheses