TABLE 2.
Cluster location | Peak (MNI) |
Number of voxels | T value | ||
x | y | z | |||
Seed: left crus I | |||||
G1 vs G0 | |||||
Left superior mPFC | −9 | 57 | −3 | 29 | 2.6298 |
G1 vs HC | |||||
Bilateral precuneus | 9 | −72 | 27 | 137 | 3.4230 |
Right inferior parietal lobule | 42 | −60 | 42 | 68 | 2.9813 |
Left superior temporal gyrus | −36 | 15 | −27 | 39 | −4.5190 |
Left middle temporal gyrus | −51 | −27 | −6 | 42 | −3.1027 |
Left inferior temporal gyrus | −51 | −9 | −30 | 40 | −3.1181 |
Right middle temporal gyrus | 45 | −3 | −27 | 49 | −3.1517 |
Seed: right crus I | |||||
G1 vs G0 | |||||
Left superior mPFC | −12 | 54 | −3 | 40 | 2.6852 |
Right posterior cingulate cortex/precuneus | 9 | −51 | 6 | 59 | 2.8385 |
Right precuneus | 39 | 21 | −30 | 46 | −2.8312 |
G1 vs HC | |||||
Right cerebellum crus II | 30 | −84 | −42 | 26 | 3.5445 |
Right middle temporal gyrus/inferior temporal gyrus | 51 | 6 | −24 | 141 | −2.9582 |
Bilateral mPFC/anterior cingulate cortex | 12 | 45 | −9 | 136 | −2.9683 |
Seed: lobule IX | |||||
G1 vs G0 | |||||
Left superior mPFC | −21 | 60 | 3 | 81 | 3.4249 |
Left superior frontal gyrus/middle frontal gyrus | −21 | 21 | 51 | 153 | 3.4111 |
Right superior frontal gyrus/middle frontal gyrus | 33 | 24 | 42 | 89 | 3.3205 |
Left angular gyrus | −45 | −69 | 36 | 139 | 2.9175 |
Right angular gyrus | 51 | −69 | 45 | 42 | 2.5483 |
Left precuneus | −6 | −72 | 48 | 26 | 2.7776 |
Right cerebellum crus I/II | 39 | −81 | −39 | 83 | 3.8131 |
G1 vs HC | |||||
Right middle frontal gyrus | 36 | 27 | 48 | 48 | 3.1125 |
Right precuneus | 9 | −69 | 24 | 28 | 3.0119 |
G1, MDD patients with gastrointestinal symptoms; G0, MDD patients without gastrointestinal symptoms; HC, healthy controls; MNI, Montreal Neurological Institute; mPFC, medial prefrontal cortex.