Table 3.

Univariate and multivariate logistic regression analysis for postoperative complications in the entire cohort.

Factors	Major PC Univariate		Major PC Multivariate		Severe PC Univariate		Severe PC Multivariate
	HR (95% CI)	P value	HR (95% CI)	P value	HR (95% CI)	P value	HR (95% CI)	P value
Age, years	1.044 (1.030-1.059)	<0.001*	1.028 (1.013-1.044)	<0.001*	1.042 (1.021-1.063)	<0.001*	1.023 (1.001-1.046)	0.039*
Sex, Male/Female	1.107 (0.756-1.369)	0.910			1.044 (0.674-1.618)	0.846
GLIM-high WL	1.298 (0.947-1.780)	0.105			1.674 (1.087-2.577)	0.019*
GLIM-low BMI	1.838 (1.286-2.628)	0.001*			1.880 (1.157-3.054)	0.011*
GLIM-low SMI	1.855 (1.408-2.444)	<0.001*	1.489 (1.110-1.997)	0.008*	1.937 (1.309-2.866)	0.001*	1.536 (1.015-2.326)	0.042*
Hemoglobin, g/L	0.990 (0.985-0.996)	<0.001*			0.994 (0.986-1.002)	0.141
Albumin, g/L	0.929 (0.903-0.956)	<0.001*	0.958 (0.929-0.988)	0.007*	0.924 (0.888-0.962)	<0.001*	0.950 (0.909-0.992)	0.020*
Charlson score
1/0	1.485 (1.083-2.037)	0.014*	1.367 (0.986-1.894)	0.061	1.420 (0.891-2.263)	0.140	1.328 (0.825-2.137)	0.243
≥2/0	2.225 (1.586-3.122)	<0.001*	1.902 (1.339-2.702)	<0.001*	2.126 (1.324-3.414)	0.002*	1.838 (1.130-2.989)	0.014*
Tumor size, cm	1.101 (1.041-1.164)	0.001*			1.099 (1.015-1.189)	0.020*
pTNM stage
II/I	1.854 (1.291-2.661)	0.001*			1.814 (1.056-3.113)	0.031*
III/I	1.577 (1.157-2.149)	0.004*			1.727 (1.083-2.755)	0.022*

PC, postoperative complication; GLIM, Global Leadership Initiative on Malnutrition; WL, weight loss; BMI, body mass index; SMI, skeletal muscle index; pTNM, pathologic tumor–node–metastasis.

^*Statistically significant.