Table 1.
Characteristics of participants in lifelines.
| Characteristics | N | n/mean ± SD /median(IQR) | Prevalence (%) |
|---|---|---|---|
| Age | 162,439 | 43.18 ± 14.92 | |
| Sex (female) | 162,439 | 94,440 | 58.14 |
| Ethnicity (white European) | 162,370 | 158,511 | 97.62 |
| Obesity | |||
| Body mass index (BMI) | 162,364 | 25.62 ± 4.63 | |
| Waist-hip-ratio (WHR) | 162,360 | 0.90 ± 0.08 | |
| Overweight | 162,364 | 86,273 | 53.14 |
| Obesity | 162,364 | 24,418 | 15.04 |
| Anxiety | |||
| Current anxiety | 158,094 | 12,238 | 7.74 |
| Sum_Anxietya | 127,380 | 0.00 (0.00–2.00) | |
| Depression | |||
| Current depression | 157,567 | 5,421 | 3.44 |
| Sum_Depressiona | 127,378 | 0.00 (0.00–1.00) | |
| Smoking | |||
| Ever-smoker | 156,073 | 79,861 | 51.17 |
| Current-smoker | 156,511 | 31,496 | 20.12 |
| Tobacco high consumption | 150,112 | 10,896 | 7.26 |
| Number of cigarette per daya | 150,112 | 0.00 (0.00–10.00) | |
| Packyearsa | 149,726 | 0.00 (0.00–8.50) | |
| Alcohol use | |||
| Current drinker | 153,269 | 116,803 | 76.21 |
| Alcohol high consumption | 153,150 | 23,847 | 15.57 |
| Daily alcohol intake (g/day)a | 153,150 | 3.44 (0.61–10.08) | |
| Drug useb | |||
| Drug ever use | 88,401 | 9558 | 10.81 |
| Soft drug ever use | 88,171 | 9314 | 10.56 |
| Hard drug ever use | 88,386 | 3207 | 3.63 |
| Drug use frequencya | 88,401 | 0.00 (0.00–0.00) | |
| Soft drug use frequencya | 88,171 | 0.00 (0.00–0.00) | |
| Hard drug use frequencya | 88,386 | 0.00 (0.00–0.00) | |
SD standard deviation, IQR interquartile range.
Definitions: Sum_Anxiety: sum score of 10 items related to anxiety from MINI, ranged from 0 to 10. Sum_Depression: sum score of 10 items related to depression from MINI, ranged from 0 to 10. Tobacco high consumption: using cigarettes ≥20 per day. 1 packyear: using 20 cigarettes per day for 1 year, or using 1 cigarette per day for 20 years. Alcohol high consumption: daily alcohol intake ≥15 grams per day. For adults, overweight: 25.0 ≤ BMI < 30.0 kg/m2; obesity: BMI ≥ 30.0 kg/m2; for children, overweight: 1.0 ≤ BMI z-score < 2.0, obesity: BMI z-score ≥ 2.0; the prevalence of overweight in the table include obesity. According to Dutch law, soft drugs include cannabis and magic mushrooms; hard drugs include amphetamine, ecstasy, heroin, cocaine and so on.
aData distribution is left skewed, using median and interquartile range to describe data.
bData on drug use for adults was assessed only in the second assessment, so the sample size of drug use was smaller than other phenotypes measured at baseline.