Table 2.

Top 5 predicted regulator effects.

Rank	Analysis (CONCvsDNT)	Consistency Score	Diseases & Functions	Regulator Total	Target Total
1	WT	14.224	Activation of myeloid cells, Activation of phagocytes, Migration of myeloid cells, Recruitment of cells	5	19
2	WT	14.199	Cell movement of granulocytes, Focal necrosis of liver, Invasion of cells, Migration of tumor cell lines	8	35
3	WT	12.728	Cell movement of carcinoma cell lines, Central nervous system solid tumor, Development of neuroepithelial tumor, Homing of cells, Stimulation of cells	13	50
4	WT	12.656	Formation of glomerular crescent	10	6
5	WT	12.603	Accumulation of phagocytes, Cell movement of carcinoma cell lines, Central nervous system solid tumor, Development of neuroepithelial tumor, Homing of cells, Stimulation of cells	10	51

IPA predicted a total of 100 regulator effects whose consistency score ranged from −15.011 (lowest) to 14.224 (highest) from DE genes comparing CONC vs DNT in WT, Ddit3^−/−, Jun^−/−, and Jun^−/− Ddit3^−/− mice.