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. 2022 Mar 16;13(3):245. doi: 10.1038/s41419-022-04671-6

Fig. 6. EPO treatment augments M2 phenotype macrophage anti-apoptosis function following LPS treatment.

Fig. 6

A Flow cytometry data shows that LPS + EPO treatment significantly attenuates % late apoptosis (Q2 quadrant) and as a result, it increases the percentage of early apoptosis (Q3 quadrant) and the live cells (Q4 quadrant) as compared to LPS treatment. None of the treatments shows positive for necrosis. BMMØs treated with LPS (50 ng/mL) for 24 h and EPO (5 IU/mL) for 72 h. B The results of apoptosis are mentioned in the bar graph. One-way ANOVA, Tukey’s multiple comparisons test. Data were expressed as means ± SEM, ****P < 0.0001, LPS vs. LPS + EPO, n = 3.