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. 2022 Mar 3;13:780966. doi: 10.3389/fneur.2022.780966

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Copyright © 2022 Huang, Lin, Huang, Cao, Jin, Wu, Fan, Tu, Huang and Jiang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Significantly altered global connectivity was observed in left- and right-sided stroke patients. A repeated measure ANCOVA with age and gender as covariates of no interest determined that (A) K_D_D [F_{(1, 57)} = 26.31, p < 0.001], (B) K_D_BC [F_{(1, 57)} = 30.82, p < 0.001], (C) K_D_CC [F_{(1, 57)} = 8.86, p = 0.004], (D) K_D_E [F_{(1, 57)} = 7.20, p = 0.01] and (E) K_D_PC [F_{(1, 57)} = 24.56, p < 0.001] of left-sided stroke patients (orange) and (A) K_D_D [F_{(1, 56)} = 13.48, p = 0.001], (B) K_D_BC [F_{(1, 56)} = 28.55, p < 0.001], (C) K_D_CC [F_{(1, 56)} = 8.16, p = 0.006], (D) K_D_E [F_{(1, 56)} = 9.70, p = 0.003] and (E) K_D_PC [F_{(1, 56)} = 24.48, p < 0.001] of right-sided stroke patients (cyan) significantly decreased compared to HCs across all link densities. Data plotted as mean ± SE.