Table 2.
Toxicity analysis of proteins and metabolites, which showed over 2-fold differences between the Crystal group and Control group.
| Ingenuity toxicity lists | a-log (p-value) | bRatio | Molecules |
|---|---|---|---|
| Acute renal failure panel (Rat) | 5.87 | 0.0806 | Anxa3,Cd14,Cd44,Lcn2,Umod |
| Persistent renal ischemia-reperfusion injury (Mouse) | 3.97 | 0.1 | Dpysl3,Havcr1,Lcn2 |
| Positive acute phase response proteins | 2.42 | 0.0667 | Hp,Serpina3 |
| Increases transmembrane potential of mitochondria and mitochondrial membrane | 1.98 | 0.04 | Lgals1, Serpina3 |
a
The –log (p-value) reflects whether the association between differentially expressed molecules and toxicity processes comes from random matching.
b
The ratio shows the extent of overlap of differentially expressed molecules with the total molecules in the Toxicity List.