Table 1.
Patient characteristics by overall mortality (N = 4,610).
|
All
(N = 4,610) |
Non-survivor
(N = 2,511) |
Survivor
(N = 2,099) |
p-value | |
|---|---|---|---|---|
| Basic characteristics | ||||
| Age, years | 66.4 ± 16.4 | 69.7 ± 15.5 | 62.5 ± 16.5 | <0.01 |
| Follow-up duration, years | 1.2 ± 1.3 | 0.4 ± 0.7 | 2.1 ± 1.3 | <0.01 |
| Male | 2,943 (63.8%) | 1,658 (66.0%) | 1,285 (61.2%) | <0.01 |
| BMI | 24.4 ± 4.7 | 24.0 ± 4.7 | 24.9 ± 4.7 | <0.01 |
| Charlson comorbidity index | 2.4 ± 1.6 | 2.7 ± 1.6 | 1.9 ± 1.5 | <0.01 |
| Active cancer | 627 (13.6%) | 523 (20.8%) | 104 (5.0%) | <0.01 |
| Severity and managements | ||||
| APACHE II score | 25.1 ± 7.5 | 27.8 ± 7.1 | 21.9 ± 6.7 | <0.01 |
| Shock | 2,134 (46.3%) | 1,500 (59.7%) | 634 (30.2%) | <0.01 |
| Ventilator | 3,391 (73.6%) | 2,074 (82.6%) | 1,317 (62.7%) | <0.01 |
| Renal replacement therapy (RRT) | ||||
| RRT initiated during ICU admission | 738 (16%) | 546 (21.7%) | 192 (9.2%) | <0.01 |
| RRT for end-stage renal disease | 130 (2.8%) | 69 (2.8%) | 61 (2.9%) | 0.75 |
| Reasons for ICU admission | ||||
| Acute cardiac disorder | 221 (4.8%) | 42 (2.6%) | 156 (7.4%) | <0.01 |
| Acute gastrointestinal disorder | 287 (6.2%) | 146 (5.8%) | 141 (6.7%) | 0.22 |
| Acute neurological disorder | 444 (9.6%) | 171 (6.8%) | 273 (13.0%) | <0.01 |
| Acute renal disorder | 124 (2.7%) | 57 (2.3%) | 67 (3.2%) | 0.06 |
| Respiratory disorder | 420 (9.1%) | 289 (11.5%) | 131 (6.2%) | <0.01 |
| Sepsis | 2,235 (48.5%) | 1,402 (55.8%) | 833 (39.7%) | <0.01 |
| Others | 879 (19.1%) | 381 (15.2%) | 498 (23.7%) | <0.01 |
| Outcomes | ||||
| ICU-stay, days | 9.9 ± 8.4 | 11.3 ± 8.8 | 8.3 ± 7.6 | <0.01 |
| Hospital-stay, days | 24.2 ± 19.0 | 26.3 ± 19.7 | 21.8 ± 17.9 | <0.01 |
| Ventilator-day, days | 9.7 ± 9.1 | 10.8 ± 9.6 | 8.1 ± 8.0 | <0.01 |
| In-hospital mortality | 1,291 (28%) | 1,291 (28%) | NA | |
| 90-day mortality | 1,741 (37.8%) | 1,741 (37.8%) | NA | |
| 1-year mortality | 2,151 (46.7%) | 2,151 (46.7%) | NA |
BMI, body mass index; APACHE II, acute physiology and chronic health evaluation; RRT, renal replacement therapy; ICU, intensive care unit; NA, not applicable.