Table 2.

Daily and cumulative fluid status in critically ill patients categorized by long-term mortality.

	All (N = 4,610)			Non-survivors (N = 2,511)			Survivors (N = 2,099)			p-valuea
	Input (I)	Output (O)	IO balance	Input (I)	Output (O)	IO balance	Input (I)	Output (O)	IO balance
Daily fluid status
Day 1	3287.6 ± 2690.9	2196.9 ± 1715.5	982.9 ± 2670.4	3745.3 ± 3056.9	2036.2 ± 1763.3	1473.7 ± 2985.6	2782.8 ± 2106.9	2371.3 ± 1644.8	395.7 ± 2090.1	<0.01
Day 2	1710.7 ± 1221.1	1841.6 ± 1376.5	−61.4 ± 1388.4	1742.3 ± 1274.2	1708.4 ± 1269.5	65.5 ± 1417.5	1674.3 ± 1156.1	1993.8 ± 1475.1	−213.2 ± 1337.3	<0.01
Day 3	1641.5 ± 970.0	2013.4 ± 1384.2	−215.7 ± 1236.4	1634.4 ± 989.7	1903.6 ± 1369.1	−136.1 ± 1301.6	1650.2 ± 945.5	2145.7 ± 1391.2	−310.9 ± 1146.6	<0.01
Day 4	1632.2 ± 1035.7	2040.5 ± 1356.7	−228.0 ± 1172.4	1619.8 ± 1048.6	1951.4 ± 1337.0	−182.3 ± 1231.7	1648.1 ± 1019	2154.3 ± 1373.5	−282.7 ± 1094.9	<0.01
Day 5	1596.0 ± 935.7	2041.3 ± 1367.4	−216.6 ± 1070.5	1595.7 ± 966.5	1957.9 ± 1351.8	−177.6 ± 1130.5	1596.4 ± 892.3	2154.5 ± 1380.8	−263.3 ± 992.2	0.01
Day 6	1619.0 ± 911.7	1979.2 ± 1285.5	−159.5 ± 985.5	1606.3 ± 942.6	1926.0 ± 1246.2	−144.2 ± 1050.0	1637.4 ± 865.3	2054.6 ± 1336.1	−177.8 ± 902.3	0.25
Day 7	1610.5 ± 954	1939.9 ± 1271.4	−126.4 ± 897.9	1624.1 ± 1014.6	1842.2 ± 1280.1	−75.9 ± 969.1	1590.1 ± 855.0	2083.5 ± 1245.3	−186.9 ± 800.4	<0.01
Cumulative fluid status
Day 1–3	6070.0 ± 3971.6	5328.4 ± 3484.3	705.8 ± 3710.0	6654.6 ± 4153.4	5075.6 ± 3409.5	1403.2 ± 4096	5427.2 ± 3656.2	5603.3 ± 3544.4	−128.4 ± 2981.3	<0.01
Day 4–7	4086.0 ± 3771.3	4993.3 ± 4711.1	−730.6 ± 2854.1	4523.5 ± 3761.8	5308.0 ± 4498.8	−580 ± 2995.6	3604.4 ± 3723.7	4650.3 ± 4910.4	−910.7 ± 2664.5	<0.01

^aComparison of IO balance between the survivors and non-survivors. Data are presented as mean ± standard deviation.