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. 2022 Mar 3;12:846760. doi: 10.3389/fonc.2022.846760

Table 3.

Subgroup analysis of risk of death between melanoma and non-melanoma group.

Non-melanoma Melanoma HR (95% CI) p value
N No. of death N No. of death
Age
 ≤54 710 7 71 7 13.08 (4.41–38.77) <0.0001
 55–69 1,430 47 143 14 2.85 (1.55–5.23) <0.001
 ≥70 2,620 571 262 72 1.33 (1.04–1.70) 0.024
p for interaction <0.0001
Sex
 Female 2,060 235 206 39 1.63 (1.16–2.29) 0.005
 Male 2,700 390 270 54 1.50 (1.13–2.00) 0.006
p for interaction = 0.6331
Monthly income (NT$)
 <20,000 1,527 231 144 34 1.76 (1.22–2.54) 0.003
 20,001–40,000 2,349 320 235 44 1.33 (0.97–1.83) 0.078
 >40,000 884 74 97 15 1.93 (1.09–3.42) 0.024
p for interaction = 0.3457
Residential region
 Northern 1,989 236 242 42 1.55 (1.12–2.16) 0.009
 Central 1,116 172 87 17 1.29 (0.78–2.13) 0.322
 Southern 1,212 171 111 27 1.82 (1.20–2.74) 0.005
 Others 443 46 36 7 1.37 (0.61–3.09) 0.447
p for interaction = 0.775
Charlson comorbidity index score
 0 2,663 158 212 25 2.40 (1.56–3.68) <0.0001
 1 1,024 156 126 21 1.22 (0.77–1.93) 0.394
 2 478 124 54 15 1.01 (0.58–1.76) 0.977
 3 280 75 45 17 1.67 (0.98–2.86) 0.060
 ≥4 315 112 39 15 1.20 (0.70–2.08) 0.509
p for interaction = 0.0799
Charlson comorbidity index score
 0 2,663 158 212 25 2.40 (1.56–3.68) <0.0001
 1 1,024 156 126 21 1.22 (0.77–1.93) 0.394
 ≥2 1,073 311 138 47 1.25 (0.92–1.71) 0.152
p for interaction = 0.029

Adjusted for age, sex, monthly income, residential region, hypertension, and hyperlipidemia.