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. 2022 Mar 3;13:839307. doi: 10.3389/fneur.2022.839307

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Copyright © 2022 Jeppsson, Bjerke, Hellström, Blennow, Zetterberg, Kettunen, Wikkelsø, Wallin and Tullberg.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Cerebrospinal fluid (CSF) biomarkers of white matter damage, astroglial response, and extracellular matrix remodeling in 52 patients with iNPH, 17 with SSVD, and 28 controls. Concentration is plotted as individual values. Bars indicate median values. Only significant values are marked. iNPH, idiopathic normal pressure hydrocephalus; SSVD, subcortical small vessel disease; NFL, Neurofilament light protein; GFAP, glial fibrillary acidic protein; MBP, myelin basic protein; MMP, matrix metalloproteinases; TIMP, tissue inhibitors of metalloproteinases. O indicates values outside the axis.