Table 2.
Results from stepwise regression examining peripheral serum cytokines that predicted clinical motor scores (i.e., tremor scores) in persons with PD, while controlling for age, disease duration, disease duration.
| Variables entered | Full Data Set (N = 26) |
Exploratory Analysis 1 (N = 23) |
Exploratory Analysis 2 (N = 16) |
||||||
|---|---|---|---|---|---|---|---|---|---|
| β | t | p | β | t | p | β | t | p | |
| Step one | |||||||||
| Age | .06 | .25 | .80 | −.09 | −.31 | .75 | .077 | .22 | .83 |
| Disease duration | .45 | 2.12 | .05 | .36 | 1.48 | .16 | .33 | 1.08 | .31 |
| Hoehn and Yahr | −.22 | −.96 | .35 | −.12 | −.45 | .65 | −.11 | −.34 | .74 |
| Step two | |||||||||
| Age | −.27 | −1.36 | .19 | −.473 | −2.07 | .05 | −.36 | −1.43 | .19 |
| Disease duration | .46 | 2.80 | .013 | .41 | 2.38 | .03 | .38 | 1.86 | .10 |
| Hoehn and Yahr IFN-γ |
−.26 −.67 |
−1.47 −3.54 |
.16 .003 |
−.13 −.76 |
−.66 −3.74 |
.52 .002 |
−.19 −.86 |
−.86 −3.66 |
.42 .006 |
| Step three | |||||||||
| Age | −0.34 | −1.99 | 0.065 | −0.51 | −2.97 | .01 | −.45 | −2.36 | .05 |
| Disease duration Hoehn and Yahr |
0.49 −0.30 |
3.63 −1.98 |
0.002 0.07 |
0.39 −0.22 |
3.00 −1.43 |
.01 .17 |
.39 −.16 |
2.58 −.99 |
.04 .35 |
| IFN-γ IL-4 |
−1.05 0.52 |
−5.14 2.89 |
0 .011 |
−1.09 0.53 |
−5.99 3.33 |
0 .006 |
−1.24 0.52 |
−5.62 2.76 |
0.001 0.02 |