Table 1.
Stage | Sheldon staging system [2] | Mayo staging system [2] | TNM staging system | |||
---|---|---|---|---|---|---|
Localized disease | I | Tumor is limited to the urachal mucosa | Tumor is confined to the urachus and/or bladder | T1 | Tumor invades the subepithelial connective tissue | |
II | Invasion confined to the urachus itself (not beyond muscle layer) | Extension beyond the muscular layer of the urachus and/or bladder | T2 | Invasion of the muscular layer of the urachus or bladder | ||
Locally advanced disease | III | IIIA | Local extension to the bladder | Metastasis to regional lymph nodes | T3 | Invasion of the perivisceral soft tissue, prostate, uterus, or vagina |
IIIB | Local extension to abdominal wall | |||||
IIIC | Invasion of the peritoneum | |||||
IIID | Invasion of the local viscera other than the bladder | |||||
Advanced disease | IV | IVA | Metastasis to lymph nodes | Metastasis to nonregional lymph nodes or other distant sites | T4 | Invasion of the abdominal wall and metastasis to lymph nodes or other distant sites |
IVB | Distant metastasis |
TNM = tumor, node, metastasis.