Table 2.
Coagulation and thrombin generation parameters
| Parameters | Control | PAN | PAN + Pio | PAN + GQ-16 | UPCr Correlation Rˆ2 | UPCr Correlation p value |
|---|---|---|---|---|---|---|
| ETP (nM∗min) | 2445 ± 402.1 | 3646 ± 198.8∗ (p = 0.0143) | 3509 ± 427.8 | 2544 ± 489.0# (p = 0.0493) | 0.2477 | 0.0133± |
| Peak Thrombin (nM) | 98.97 ± 20.82 | 180.4 ± 27.02 (p = 0.0698) | 180.8 ± 29.50 | 134.0 ± 35.54 | 0.0282 | 0.4328 |
| Velocity Index (nM/min) | 16.08 ± 5.073 | 33.07 ± 8.570 | 34.67 ± 8.448 | 19.91 ± 6.643 | 0.0037 | 0.7775 |
| Lag Phase (min) | 10.38 ± 0.826 | 6.321 ± 0.713∗∗(p = 0.006) | 7.714 ± 0.6974 | 9.250 ± 1.532 (p = 0.0956) | 0.2035 | 0.0269± |
∗
p < 0.05; compared to Control.
∗∗
p < 0.01; compared to Control.
#
p < 0.05; compared to PAN.
±
p < 0.05; correlation.