Fig. 4.

Bioinformatics analysis of upregulated and downregulated exoDEPs. (A) GO annotation includes Biological Processes (BP), Cellular component (CC) and Molecular Function (MF) analysis. Coloring of proteins is based on functional enrichment analysis; (B) The enriched pathways by KEGG analysis; (C) Visible clusters of the protein-protein interaction map was assigned to enriched ontologies among the upregulated and downregulated exoDEPs with calculated P-value adjusted for multiple comparisons.