Table 1:
Summary of sample for individuals from 1,162 families from the Collaborative Study on the Genetics of Alcoholism (COGA) data used in the current study.
| Total | # AUD cases | # controls | # with DSM-5 AUD diagnostic criterion count | |
|---|---|---|---|---|
| Male | 3,762 | 2,041 | 422 | 3,400 |
| Female | 4,138 | 1,410 | 1,194 | 3,803 |
| Birth cohort1 | 325 | 82 | 173 | 307 |
| Birth cohort2 | 1,216 | 489 | 462 | 1,188 |
| Birth cohort3 | 2,869 | 1,617 | 515 | 2,804 |
| Birth cohort4 | 3,490 | 1,263 | 466 | 2,904 |
| FH+ | 4,842 | 2,531 | 669 | 4,639 |
| FH? | 2,722 | 850 | 840 | 2,280 |
| FH− | 336 | 72 | 107 | 284 |
Note: Alcohol Use Disorder (AUD) was defined as a lifetime diagnosis of DSM-IV alcohol dependence or DSM-5 alcohol use disorder; Controls were individuals aged 21 years or older who had consumed alcohol but did not meet criteria for alcohol or drug use disorders during their lifetimes.