[A] In-vitro wound healing assay images of (a) HaCaT cells obtained at 0, 24 and 48 h after wound creation, (b) L929 cells obtained at 0, 12 and 24 h. Scale bar: 100 μm. [B] Percentage wound closure graph of (a) HaCaT cells and (b) L929 cells. Results expressed as mean ± SD (n = 3, ∗P < 0.05). Treatments: Control (0.1 M PBS, pH 7.4), LLKKK18 – Chitosan NP (LLKKK18 peptide entrapped Chitosan nanoparticles), Tylotoin – Chitosan MP (Tylotoin peptide entrapped Chitosan microparticles), PLGA/Collagen-NF (PLGA/Collagen nanofibers), NF-NP-MP (Bioactive peptides laden nano/micro-sized particles enriched PLGA/Collagen nano-fiber mat).