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. 2022 Mar 4;94(10):4343–4351. doi: 10.1021/acs.analchem.1c05068

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© 2022 The Authors. Published by American Chemical Society

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Extracted ion chromatograms for glycan composition H1N1 (m/z 504.219). Three differently eluting H1N1 isomers (a, b, and c) were observed in (A) the HEK293^WT and (B) N/TERT-1^WT samples. The (C) HEK293^{B4GALT1/2/3/4 KO}, (D) N/TERT-1^EOGT KO, and (E) N/TERT-1^C1GALT1 KO samples aided in the annotation of these isomers, in combination with MS fragmentation (Supporting Figures S1 and S2).