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. 2022 Mar 3;16:804743. doi: 10.3389/fnint.2022.804743

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Copyright © 2022 Guerrero-Gonzalez, Surgent, Adluru, Kirk, Dean, Kecskemeti, Alexander and Travers.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Quantitative analysis of original and optimized pipelines using brainstem white matter regions of interest. (A) Comparison of coefficient of variation in the original and optimized pipelines. (B) Proportion of age trajectory variance (R²) explained by apparent fiber density (AFD) in each white matter tract.