(a) Schematic diagram
of the exploratory experiment: the experiment
was divided into three stages. The first stage compared the thrombus
induction efficiency of 30, 40, 50, and 60% ferric chloride-soaked
filter wrapped around the right carotid artery for 10 and 20 min.
The second stage compared the efficiency of thrombus induction when
50% ferric chloride was exposed to the right carotid artery for 3,
5, 8, and 10 min. The third stage investigated the thrombolytic effect
of rt-PA injected at 1.5 and 3 h after the induction of thrombosis
for different exposure times. (b) shows the rat carotid artery as
viewed under the microscope. The black arrow indicates the dissected
carotid artery; a ferric chloride-soaked filter paper wrapped around
the carotid artery after operation. (c) Doppler blood flow imaging,
camera image, and laser speckle images.