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. 2022 Mar 3;12:803031. doi: 10.3389/fmicb.2021.803031

FIGURE 7.

FIGURE 7

The SARS-CoV-2-specific T-cell response correlated with antibody levels 17–18 months after infection. IFN-γ- and IL-2-secreting T-cell responses and antibody (ND50, anti-S IgG, and anti-N IgG) levels were performed in COVID-19 convalescent patients 17–18 months after illness onset. (A) Correlation of ND50 and SARS-CoV-2-specific IFN-γ-secreting T cells (N = 45). (B) Correlation of ND50 and SARS-CoV-2-specific IL-2-secreting T cells (N = 16). (C) Correlation of anti-S IgG levels and SARS-CoV-2-specific IFN-γ-secreting T cells (N = 45). (D) Correlation of anti-S IgG levels and SARS-CoV-2-specific IL-2-secreting T cells (N = 16). (E) Correlation of anti-N IgG levels and SARS-CoV-2-specific IFN-γ-secreting T cells (N = 45). (F) Correlation of anti-N IgG levels and SARS-CoV-2-specific IL-2-secreting T cells (N = 16). A two-sided Spearman rank correlation test was used to evaluate the correlation between SARS-CoV-2-specific T-cell responses and antibody levels.