. Author manuscript; available in PMC: 2022 Aug 1.

Published in final edited form as: Obesity (Silver Spring). 2021 Jul 5;29(8):1328–1337. doi: 10.1002/oby.23201

TABLE 2.

Basal ganglia volumes and DBSI metrics In people-with-obesity and people-with-normal-weight groups

	People with obesity (n = 25)	People with normal weight (n = 21)	p value
Caudate
Volume (mm³)	3,590 (268)	3,766 (438)	0.006^***
DBSI fiber fraction	0.31 (0.02)	0.31 (0.02)	0.8
DBSI nonrestricted fraction	0.42 (0.03)	0.40 (0.03)	0.01^***
DBSI restricted fraction	0.083 (0.01)	0.076 (0.01)	0.17
Globus pallidus
Volume (mm³)	1,774 (114)	1,791 (149)	0.06
DBSI fiber fraction	0.59 (0.06)	0.57 (0.05)	0.11
DBSI nonrestricted fraction	0.17 (0.04)	0.2 (0.05)	0.12
DBSI restricted fraction	0.170 (0.03)	0.155 (0.03)	0.33
Nucleus accumbens
Volume (mm³)	518 (68)	501 (88)	0.048^*
DBSI fiber fraction	0.39 (0.06)	0.47 (0.05)	<0.0001^***
DBSI nonrestricted fraction	0.44 (0.05)	0.39 (0.06)	<0.0001^***
DBSI restricted fraction	0.095 (0.02)	0.092 (0.02)	0.81
Putamen
Volume (mm³)	4,994 (405)	5,056 (351)	0.22
DBSI fiber fraction	0.36 (0.02)	0.39 (0.02)	0.0005^***
DBSI nonrestricted fraction	0.45 (0.03)	0.45 (0.03)	0.71
DBSI restricted fraction	0.127 (0.02)	0.108 (0.01)	0.004^***

Average volumes and average DBSI metrics were compared between people with obesity and people with normal weight using a multiple linear regression model with age, sex, race, and level of education as covariates. Volumes were normalized for total intracranial volume. Means (SD) are reported.

Abbreviation: DBSI, diffusion basis spectrum imaging.

p ≤ 0.05

^***

p ≤ 0.01.