Table 2. Experimental and Fitted Solubility Data of MET·HCl in Water + Acetonitrile (P = 0.1 MPa)^a,b.

	103x1exp	103x1apelblat	103x1CNIBS	103x1AJA	103x1λh
283.15 K
0.30	3.730	3.656	3.825	3.394	3.648
0.40	7.404	7.356	6.648	7.137	7.154
0.50	9.214	9.898	10.84	11.94	11.07
0.60	17.61	17.43	16.26	17.09	17.16
0.70	22.86	22.85	22.14	21.99	23.05
0.80	26.14	25.62	27.20	26.20	25.76
0.90	30.29	29.75	30.16	29.15	30.92
1.00	30.45	30.27	30.36	29.89	31.26
288.15 K
0.30	3.861	4.016	3.872	3.823	4.019
0.40	8.137	8.103	8.035	7.995	8.019
0.50	13.15	11.94	13.38	13.36	12.54
0.60	18.93	19.27	19.06	19.14	19.16
0.70	25.49	25.49	24.40	24.70	25.58
0.80	27.56	28.58	28.96	29.56	28.67
0.90	33.17	34.04	32.37	33.07	34.72
1.00	33.85	34.32	34.01	34.15	34.62
293.15 K
0.30	4.530	4.407	4.504	4.292	4.418
0.40	8.710	8.945	8.875	8.922	8.963
0.50	14.95	14.11	14.73	14.88	14.15
0.60	21.39	21.30	21.35	21.32	21.33
0.70	28.21	28.31	27.85	27.58	28.30
0.80	32.03	31.78	33.39	33.13	31.81
0.90	38.59	38.50	37.31	37.24	38.45
1.00	38.75	38.66	39.09	38.69	38.63
298.15 K
0.30	4.688	4.831	4.687	4.802	4.847
0.40	9.941	9.894	9.920	9.919	9.989
0.50	16.43	16.34	16.55	16.50	15.91
0.60	23.62	23.54	23.65	23.64	23.67
0.70	31.50	31.33	30.64	30.63	31.24
0.80	35.61	35.21	37.09	36.89	35.19
0.90	43.16	43.10	42.12	41.63	42.46
1.00	43.60	43.25	43.83	43.49	42.97
303.15 K
0.30	5.517	5.290	5.510	5.355	5.308
0.40	11.11	10.96	11.11	10.99	11.10
0.50	18.07	18.57	18.18	18.22	17.84
0.60	25.98	26.02	25.88	26.09	26.21
0.70	34.43	34.53	33.60	33.84	34.40
0.80	39.06	38.89	40.81	40.85	38.84
0.90	47.83	47.76	46.48	46.25	46.77
1.00	48.33	48.09	48.65	48.53	47.66
308.15 K
0.30	5.834	5.787	5.833	5.956	5.804
0.40	12.28	12.17	12.24	12.13	12.31
0.50	19.97	20.73	20.23	20.05	19.95
0.60	28.88	28.76	28.66	28.67	28.95
0.70	37.81	37.94	36.93	37.20	37.79
0.80	42.75	42.83	44.66	44.97	42.76
0.90	52.37	52.43	50.93	51.04	51.39
1.00	53.25	53.17	53.59	53.77	52.71
313.15 K
0.30	6.261	6.324	6.257	6.604	6.336
0.40	13.43	13.53	13.42	13.36	13.62
0.50	22.10	22.77	22.30	21.97	22.24
0.60	31.74	31.78	31.60	31.38	31.90
0.70	41.75	41.54	40.73	40.70	41.44
0.80	47.20	47.03	49.31	49.25	46.97
0.90	57.67	57.05	56.09	56.01	56.35
1.00	57.72	58.46	58.09	59.18	58.15
318.15 K
0.30	6.739	6.90	6.742	7.303	6.908
0.40	15.03	15.06	14.96	14.66	15.05
0.50	24.68	24.62	24.99	24.01	24.73
0.60	35.20	35.11	35.00	34.20	35.09
0.70	45.31	45.33	44.31	44.33	45.34
0.80	51.00	51.50	52.94	53.66	51.49
0.90	61.76	61.56	60.36	61.11	61.65
1.00	63.98	63.94	64.31	64.73	63.98
323.15 K
0.30	7.65	7.531	7.669	8.056	7.522
0.40	16.77	16.78	16.60	16.04	16.58
0.50	27.20	26.23	27.60	26.14	27.44
0.60	38.67	38.78	38.59	37.14	38.51
0.70	49.28	49.33	48.55	48.08	49.53
0.80	56.44	56.24	57.37	58.19	56.34
0.90	65.34	65.90	64.90	66.32	67.32
1.00	69.87	69.59	69.95	70.39	70.25

^ax₁ is the experimental solubility; the x₁^apelblat, x₁^CNIBSx₁^λh, and x₁^AJA are the calculated mole solubilities according to the modified Apelblat model, CNIBS/R-K model, λh model, and Apelblat–Jouyban–Acree model, respectively. represents the initial mole fraction of water in the binary aqueous solvent.

^bThe standard uncertainty is u(T) = 0.1 K; the relative standard uncertainties u_r are u_r(P) = 0.01, u_r(x₁) = 0.05, and u_r() = 0.001.