Table 5. Values of HSPs of MET·HCl and the Selected Solvents^a.

	δd (Mpa)0.5	δp (Mpa)0.5	δh (Mpa)0.5	δmix (Mpa)0.5
Water + DMF
0.30	17.24	13.91	14.11	26.26
0.40	17.16	14.01	15.46	27.01
0.50	17.06	14.13	17.15	28.02
0.60	16.93	14.30	19.32	29.40
0.70	16.77	14.51	22.21	31.38
0.80	16.53	14.81	26.25	34.37
0.90	16.18	15.26	32.28	39.20
1.00	15.60	16.00	42.30	47.84
Water + Acetonitrile
0.30	15.34	17.74	10.76	25.80
0.40	15.36	17.63	12.86	26.68
0.50	15.38	17.49	15.37	27.90
0.60	15.40	17.32	18.43	29.61
0.70	15.43	17.11	22.23	32.02
0.80	15.47	16.84	27.08	35.44
0.90	15.53	16.49	33.47	40.41
1.00	15.60	16.00	42.30	47.84
Water + n-Propanol
0.30	15.96	7.660	19.73	26.51
0.40	15.94	8.070	20.84	27.46
0.50	15.92	8.590	22.23	28.66
0.60	15.89	9.240	24.01	30.24
0.70	15.86	10.11	26.36	32.38
0.80	15.80	11.31	29.62	35.42
0.90	15.73	13.10	34.44	40.06
1.00	15.60	16.00	42.30	47.84
Solute and Pure Solvents
water	15.60	16.00	42.30	47.84
acetonitrile	15.30	18.00	6.100	24.40
n-propanol	16.00	6.800	17.40	24.60
DMF	17.40	13.70	11.30	24.86

^aδ_d: dispersion solubility parameter. δ_p: polar solubility parameter. δ_h: hydrogen bond solubility parameter. δ_mix: the total Hansen solubility parameter.