Table 3.

Multivariable analysis of non-recent HIV infections including interaction term between GISD¹ and city size (only MSM²)

	n = 6511
	Countryside (< 100 k residents)			Town/Major city (≥ 100 k residents)
	n (%)†	aPR [95% CI]‡	p-value	n (%)†	aPR [95% CI]‡	p-value
GISD1
Low deprivation	234 (59.9%)	1		815 (62.2%)	1
Medium deprivation	1090 (64.7%)	1.09 [1.01, 1.18]	0.033	1521 (60.4%)	0.97 [0.92, 1.03]	0.350
High deprivation	251 (68.8%)	1.16 [1.05, 1.28]	0.004	147 (61.8%)	1.00 [0.92, 1.09]	0.953

¹GISD German Index of Socioeconomic Deprivation, ²MSM Men who have sex with men

^†Strata specific number and proportion of non-recent infections at the time of diagnosis

^‡Prevalence ratios with corresponding 95% confidence intervals of non-recent infections at the time of diagnosis were calculated for the exposure variable GISD using multivariable Poisson regression with ZIP code cluster-robust error variance (standard errors were adjusted for 626 clusters). The model was stratified for MSM and adjusted for the variables of approximated age at the time of infection, region of origin and city size. For simplicity purposes, only strata specific effect estimates of the GISD conditional on countryside vs. town/major city are depicted. The effect estimates of the remaining covariates are nearly identical as presented in Table 2 in the MSM stratum