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. 2022 Mar 16;22:124. doi: 10.1186/s12876-022-02186-0

Table 2.

Serum ceruloplasmin levels in WD children with different manifestations at diagnosis

WD patients Cp (mg/dL) Age (years) No. of patients
Total 0–5 5–10 10–15 15–20  ≥ 20
Asymptomatic WD 5.5 ± 4.6a 5.4 ± 2.3b 261 157 67 22 9 6
Symptomatic WD 7.0 ± 4.8 9.4 ± 2.6 56 27 11 14 4 0
WD w/o ALF 5.6 ± 4.6c 6.0 ± 2.8d 302 180 75 30 11 6
WD w/ ALF 9.3 ± 4.7 9.0 ± 2.2 15 4 3 6 2 0
Total 5.7 ± 4.7 5.7 ± 4.7 317 184 78 36 13 6

WD, Wilson’s disease; ALF, acute liver failure

aRepresents comparison of serum ceruloplasmin in asymptomatic WD with symptomatic WD children, p value < 0.05

bRepresents comparison of age in asymptomatic WD with symptomatic WD children, p value < 0.001

cRepresents comparison of serum ceruloplasmin between WD children with and without acute liver failure, p value < 0.01

dRepresents comparison of age between WD children with and without acute liver failure, p value < 0.001