Table 4.

Serum ceruloplasmin levels in WD children carrying R778L mutation

Genotype	Age (years)	Cp (mg/dL)	No. of patients
			Total	0–5	5–10	10–15	15–20	≥ 20
R778L homozygotes	5.7 ± 3.1	2.3 ± 0.5*	9	9	0	0	0	0
R778L heterozygotes	6.2 ± 3.0	5.2 ± 4.5	97	64	21	6	3	3
No R778L	6.1 ± 2.8	6.1 ± 4.8	207	108	57	29	10	3
Total	6.1 ± 2.9	5.7 ± 4.7	313	181	78	35	13	6

WD, Wilson’s disease; Cp, ceruloplasmin

*Represents statistical significance of serum ceruloplasmin between WD children with and without R778L, p value < 0.05