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. 2022 Mar 3;13:821406. doi: 10.3389/fgene.2022.821406

TABLE 3.

Various GO terms and pathways related to rumen development shown from different modules.

GO term/pathway ID Gene Module
Cell division GO: 0051301 CCNB1, CCNB2 Lightgreen
Mitochondrial matrix GO: 0005759 BDH1 Darkred
Mitochondrial inner membrane GO: 0005743 HMGCL, HMGCS2, ACAT1 Darkred, lightgreen
Histone acetyltransferase complex GO:0000123 CREBBP Turquoise
Histone acetyltransferase activity GO:0004402 CREBBP Turquoise
Positive regulation of MAPK cascade GO: 0043410 IGF2 Cyan
Regulation of multicellular organism growth GO: 0040014 IGF1 Cyan
Positive regulation of phosphatidylinositol 3-kinase signaling GO: 0014068 IGF1 Cyan
Cell cycle bta04110 CCNB1, CCNB2, CREBBP Lightgreen
Butanoate metabolism bta00650 HMGCL, BDH1, ACAT1, HMGCS2 Darkred, lightgreen
Wnt signaling pathway bta04310 CREBBP Turquoise
MAPK signaling pathway bta04010 IGF1, IGF2 Cyan
Synthesis and degradation of ketone bodies bta00072 HMGCL, BDH1, ACAT1, HMGCS2 Darkred, lightgreen
PI3K-Akt signaling pathway bta04151 IGF1, IGF2 Cyan
TGF-beta signaling pathway bta04350 CREBBP Turquoise