Domain	Risk of bias			Support for judgement	Location in text (pg & ¶/fig/table)
	Low risk	High risk	Unclear
Random sequence generation (selection bias)
Allocation concealment (selection bias)
Blinding of participants and personnel (performance bias)				Outcome group: mortality
				Outcome group: non‐fatal cardiac events/AF
				Outcome group: stroke/TIA
				Outcome group: renal failure
				Outcome group: participant‐reported outcomes incl time to return to work
Blinding of outcome assessment (detection bias)				Outcome group: mortality
(if required)				Outcome group: non‐fatal cardiac events/AF
				Outcome group: stroke/TIA
				Outcome group: renal failure
				Outcome group: participant‐reported outcomes
Incomplete outcome data (attrition bias)				Outcome group: mortality
				Outcome group: non‐fatal cardiac events/AF
				Outcome group: stroke/TIA
				Outcome group: renal failure
				Outcome group: participant‐reported outcomes
Selective outcome reporting? (reporting bias)
Other bias
Notes: