. Author manuscript; available in PMC: 2022 Oct 4.

Published in final edited form as: Exp Clin Psychopharmacol. 2021 Jul 19;30(5):673–681. doi: 10.1037/pha0000492

Table 3.

Significant Associations of Candidate Genetic Variants with Tobacco Withdrawal Phenotypes

	Genetic Variant Information								Association

Phenotype	RS ID	Chrom	Ref Allele	Alt Allele	MAF	Nearest Gene(s)	Annotation	Genotyped or Imputed	B	SE	P


Confusion^a	rs2471711	4	C	T	0.037	AC097480.1/ AC097480.2	NC Int	Imputed	−0.264	0.088	.0028^*

Impulsivity^b	rs11915747	3	C	G	0.269	CADM2	Int	Imputed	0.092	0.028	.0010^*

Note. Chrom: Chromosome number location. Ref: Reference, Alt: alternate, MAF: Minor Allele Frequency; NC: Non-Coding; Int: Intronic. N/A: Not Applicable. B: unstandardized regression coefficient. SE: standard error of coefficient.

Deprivation-induced changes in Profile of Mood States confusion subscale (range 0-4)

Current Impulsivity Scale (range 0-4)

P < 0.05 after P_ACT correction over the set of correlated phenotypes.