Table 1.
Effect of cagA copy number and cagY recombination on induction of IL-8 secretion in AGS cells, in 4-week mice output colonies
| |
4-week output colonies |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| WT (N = 72) | Il10−/− (N = 82) | |||||||||
| predictors | B | SE | β | t | P | B | SE | β | t | P |
| cagA copy number | 0.073 | 0.014 | 0.476 | 5.104 | < 0.001 | 0.048 | 0.015 | 0.171 | 3.180 | 0.002 |
|
cagY recombination (cagY-S = 0, cagY-D = 1) |
−0.189 | 0.042 | −0.422 | −4.522 | < 0.001 | −0.626 | 0.041 | −0.815 | −15.190 | < 0.001 |
| constant | 0.798 | 0.043 | 18.506 | < 0.001 | 0.908 | 0.042 | 21.643 | < 0.001 | ||
| adjusted R2 = 0.383, F = 23.028, P < .001 | adjusted R2 = 0.818, F = 182.741, P < .001 | |||||||||
B: unstandardized coefficient; SE: standard error of unstandardized coefficient; β: standardized coefficient. Boldface numbers indicate P values less than 0.05.