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. 2022 Mar 15;11(1):829–840. doi: 10.1080/22221751.2022.2048969

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© 2022 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 5. — The portion of neutralizing epitopes targeted by booster vaccinations. (a) The portion of neutralizing antibody titre compared to total anti-S + N antibody for I-I-I and I-I-S groups. (b) The portion of neutralizing antibody titre compared to total anti-RBD antibody for I-I-I and I-I-S groups. The portion of neutralizing antibodies represented by monoclonal antibodies 13G2 (c) and 08B3 (d) compared to neutralizing antibody for I-I-I and I-I-S groups at D14 post booster vaccination. n = 20 in I-I-I, n = 25 in I-I-S. ns, not significant; *P < 0.05, ***P < 0.001, ****P < 0.0001.