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SerpinA3N increases the activation of Akt signaling pathway. Primary neuronal cultures were subjected to OGD/R with or without serpinA3N treatment. Western blot analysis of (A) Akt phosphorylation and (B) mTOR phosphorylation 4 h after OGD/R. N = 6. ** and ****p < 0.01 and 0.0001. Mice were injected with AAV‐null‐ZsGreen or AAV‐serpinA3N‐ZsGreen. (C) Western blot analysis of Akt phosphorylation and mTOR phosphorylation 30 h after t‐MCAO. N = 6. ** and ****p < 0.01 and 0.0001
