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Ketogenic diet mechanism of action as a cancer therapy, (→), activation; (┬), inhibition; MMP-9, matrix metalloproteinases-9; TNF-α, tumor necrosis factor alpha; HDAC, histone deacetylases; PKM2, pyruvate kinase M2; AMP-K, AMP-activated protein kinase; IL-1B, interleukin 1 beta; IF-γ, interferon gamma; NF-kB, nuclear factor kappa B.
