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Resveratrol and estradiol ameliorated aortic calcification in ovariectomized rats, as shown by Alizarin red-stained sections. (A) The sham group showing tunica intima (arrow) and tunica media (M). (B) OVX rats showing marked calcium deposition (*) in the tunica media (M). (C) Estradiol-treated rats. (D) Resveratrol-treated rats. (E) Aortic calcification percentage. Graph shows mean ± SD. Scale bar 20 μm. OVX: ovariectomized rats; E2: estradiol; Res: resveratrol.
