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Changes in myelin gene expression by farnesol. After transfection of pCMV-myc-PMP22 or pCMV-myc vector into RT4 cells, cells were treated with 0.01 μM and 0.1 μM of farnesol for 48 h. (A) Oct6 mRNA levels were determined by RT-PCR. (B) Changes in MPZ mRNA levels were determined by RT-PCR. ** p < 0.01; *** p < 0.001.
